What sequence describes the central dogma of molecular biology?

• A. RNA → DNA → Protein
• B. DNA → RNA → Protein
• C. DNA → Protein → RNA
• D. Protein → RNA → DNA

Answer: (B)

The sequence describes how genetic information moves from DNA to RNA to protein through transcription then translation. DNA serves as the template for transcription, where RNA polymerase makes messenger RNA. The mRNA then provides the code for ribosomes to assemble a protein during translation, with tRNA bringing the appropriate amino acids. This flow—DNA to RNA to protein—is the standard path for gene expression, which is why that sequence is correct.

The other sequences would imply steps that don’t align with this typical flow: RNA to DNA to Protein would require reverse transcription as the primary path, which isn’t the general rule in most cells; skipping the RNA stage or reversing the order would break how information is normally transferred in biology.