Phase 1 Clinical Trial is best described as which of the following?

• A. Phase 1 Clinical Trial
• B. Phase 2 Clinical Trial
• C. Mammalian cells
• D. Ethics

Answer: (A)

Phase 1 trials are the first stage of testing in humans and are focused on safety and dosing. They study how the drug is absorbed, distributed, metabolized, and excreted (pharmacokinetics), how it affects the body (pharmacodynamics), and what doses are tolerable, using a small number of participants. This helps establish an initial safety profile and the maximum tolerated dose before any larger tests of effectiveness. The other options describe different ideas: Phase 2 focuses on efficacy and broader safety in more people, mammalian cells refer to preclinical work in cell or animal models, and ethics concerns the oversight and approval process rather than describing a trial itself.